JPH0217555B2 - - Google Patents

Info

Publication number
JPH0217555B2
JPH0217555B2 JP54107550A JP10755079A JPH0217555B2 JP H0217555 B2 JPH0217555 B2 JP H0217555B2 JP 54107550 A JP54107550 A JP 54107550A JP 10755079 A JP10755079 A JP 10755079A JP H0217555 B2 JPH0217555 B2 JP H0217555B2
Authority
JP
Japan
Prior art keywords
parts
culture
methanol
oil
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP54107550A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5632481A (en
Inventor
Hiroshi Takiguchi
Hiroshi Mishima
Shinjiro Yamamoto
Micha Terao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14462018&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0217555(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP10755079A priority Critical patent/JPS5632481A/ja
Priority to US06/179,479 priority patent/US4346171A/en
Priority to IL60861A priority patent/IL60861A/xx
Priority to CH636680A priority patent/CH645899A5/de
Priority to MX808989U priority patent/MX6259E/es
Priority to ES494435A priority patent/ES8106177A1/es
Priority to FR8018352A priority patent/FR2463773A1/fr
Priority to SU802968603A priority patent/SU1011055A3/ru
Priority to HU802085A priority patent/HU189473B/hu
Priority to NZ194742A priority patent/NZ194742A/xx
Priority to BR8005337A priority patent/BR8005337A/pt
Priority to AU61668/80A priority patent/AU536200B2/en
Priority to DE19803031756 priority patent/DE3031756A1/de
Priority to IT8068315A priority patent/IT1209436B/it
Priority to NL8004791A priority patent/NL8004791A/nl
Priority to GB8027586A priority patent/GB2056986B/en
Publication of JPS5632481A publication Critical patent/JPS5632481A/ja
Priority to AU30814/84A priority patent/AU574695B2/en
Publication of JPH0217555B2 publication Critical patent/JPH0217555B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP10755079A 1979-08-23 1979-08-23 Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent Granted JPS5632481A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
JP10755079A JPS5632481A (en) 1979-08-23 1979-08-23 Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US06/179,479 US4346171A (en) 1979-08-23 1980-08-18 Fermentation process for producing compound having anthelmintic and acaricidal activities
IL60861A IL60861A (en) 1979-08-23 1980-08-19 Compound b-41d obtained from microorganisms of the genus streptomyces,process for the preparation thereof and process for the preparation of anthelmintic,insecticidal and acaricidal compositions containing it
MX808989U MX6259E (es) 1979-08-23 1980-08-22 Un procedimiento microbiologico para la obtencion del compuesto b-41d
HU802085A HU189473B (en) 1979-08-23 1980-08-22 Acaricide composition containing compound b-41d as active substance and process for preparing the active substance
DE19803031756 DE3031756A1 (de) 1979-08-23 1980-08-22 Verbindung b-41d, verfahren zu ihrer herstellung und diese verbindung enthaltende mittel
ES494435A ES8106177A1 (es) 1979-08-23 1980-08-22 Un procedimiento para la preparacion de nuevos antibioticos de milbecina.
FR8018352A FR2463773A1 (fr) 1979-08-23 1980-08-22 Compose ayant des activites acaricides et anthelmintiques obtenu par culture d'un micro-organisme du genre streptomyces
SU802968603A SU1011055A3 (ru) 1979-08-23 1980-08-22 Способ получени вещества,обладающего противоклещевой и глистогонной активностью
CH636680A CH645899A5 (de) 1979-08-23 1980-08-22 Verbindung mit anthelminthischer und akarizider wirkung.
NZ194742A NZ194742A (en) 1979-08-23 1980-08-22 Compound b-41d preparation by culturing a streptomyces micro-organism anthelmintic and acaricidal compositions
BR8005337A BR8005337A (pt) 1979-08-23 1980-08-22 Composicao acaricida e processo de preparar a mesma
AU61668/80A AU536200B2 (en) 1979-08-23 1980-08-22 Compound having anthelmintic and acaricidal activities
IT8068315A IT1209436B (it) 1979-08-23 1980-08-25 Composto avente struttura simile agli antibiotici milbemicine,adattivita'antielmintica ed acaricida
NL8004791A NL8004791A (nl) 1979-08-23 1980-08-25 Verbinding met anthelminthische en acaricide werking.
GB8027586A GB2056986B (en) 1979-08-23 1980-08-26 Anthelmintic and acaricidal compound
AU30814/84A AU574695B2 (en) 1979-08-23 1984-07-18 B-41 milbemycim compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10755079A JPS5632481A (en) 1979-08-23 1979-08-23 Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP6174186A Division JPS61216699A (ja) 1986-03-19 1986-03-19 抗生物質ｂ―４１ｄの製法

Publications (2)

Publication Number Publication Date
JPS5632481A JPS5632481A (en) 1981-04-01
JPH0217555B2 true JPH0217555B2 (en]) 1990-04-20

Family

ID=14462018

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10755079A Granted JPS5632481A (en) 1979-08-23 1979-08-23 Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent

Country Status (16)

Country Link
US (1) US4346171A (en])
JP (1) JPS5632481A (en])
AU (2) AU536200B2 (en])
BR (1) BR8005337A (en])
CH (1) CH645899A5 (en])
DE (1) DE3031756A1 (en])
ES (1) ES8106177A1 (en])
FR (1) FR2463773A1 (en])
GB (1) GB2056986B (en])
HU (1) HU189473B (en])
IL (1) IL60861A (en])
IT (1) IT1209436B (en])
MX (1) MX6259E (en])
NL (1) NL8004791A (en])
NZ (1) NZ194742A (en])
SU (1) SU1011055A3 (en])

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0341848U (en]) * 1989-08-31 1991-04-22

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE21984T1 (de) * 1981-10-06 1986-09-15 Ici Plc Verfahren zur bekaempfung von nematodenschaedlingen der pflanzen und zusammensetzungen dafuer.
US4597969A (en) * 1982-04-05 1986-07-01 Merck Sharp & Dohme Stabilization of unstable drugs or food supplements
NZ204074A (en) * 1982-05-10 1986-05-09 Merck & Co Inc Synergistic compositions containing avermectins
JPS5920285A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−二塩基酸エステル誘導体及びその塩
JPS60141293A (ja) * 1983-12-28 1985-07-26 Kitasato Inst:The 新規制癌性抗生物質８１−４８４およびその製造法
US5169956A (en) * 1984-06-05 1992-12-08 American Cyanamid Company Macrolide antibiotic compounds
EP0165900A3 (de) * 1984-06-08 1986-05-28 Ciba-Geigy Ag Neue Lactone, Verfahren zu ihrer Herstellung und ihre Verwendung in der Schädlingsbekämpfung
AU574852B2 (en) * 1984-10-26 1988-07-14 Sankyo Company Limited 13 - acyloxy - 5 - ketomilbemycin derivatives and preparation of 13 - hydroxy - 5 - ketomilbemycin derivatives
US5208349A (en) * 1984-10-26 1993-05-04 Sankyo Company, Limited Process for preparing milbemycin derivatives and certain novel compounds employed therein
US4857509A (en) * 1985-01-22 1989-08-15 Ciba-Geigy Corporation 13β-alkylmilbemycin derivatives for controlling parasites of animals and plants
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541
JPS6289685A (ja) * 1985-05-31 1987-04-24 Sankyo Co Ltd １３−ハロゲンミルベマイシン誘導体
US5183749A (en) * 1987-02-04 1993-02-02 Sankyo Company, Ltd. Microbial process for the preparation of milbemycin derivatives
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) * 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
DE3836586A1 (de) * 1988-10-27 1990-05-03 Ciba Geigy Ag Phlegmatisierte chinondiazid-verbindungen
JPH085393B2 (ja) * 1989-06-28 1996-01-24 いすゞ自動車株式会社 油圧アクチユエータの応答遅れ吸収装置
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
EP0524686A1 (en) * 1991-07-23 1993-01-27 Merck & Co. Inc. A process for the 14a-hydroxylation of avermectin compounds
US5276033A (en) * 1991-12-18 1994-01-04 Sankyo Company, Limited 13-(substituted thio)acetoxymilbemycin derivatives, their preparation and their agrochemical uses
US5439924A (en) * 1991-12-23 1995-08-08 Virbac, Inc. Systemic control of parasites
AU660205B2 (en) 1991-12-23 1995-06-15 Virbac, Inc Systemic control of parasites
JP2952265B2 (ja) * 1993-11-29 1999-09-20 井筒屋化学産業株式会社 松類の枯損防止用組成物及び防止方法
US5614470A (en) * 1994-04-01 1997-03-25 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use
ATE199628T1 (de) * 1995-02-24 2001-03-15 Novartis Erfind Verwalt Gmbh Zusammensetzung zur bekämpfung von parasiten
CZ288178B6 (en) * 1995-09-29 2001-05-16 Sankyo Co Milbemycin-5-oxime derivatives substituted in position 13-, and their use
AU4139797A (en) * 1997-06-09 1998-12-30 Nauchno-Proizvodstvennoye Obiedinenie "Farmbiomed" (streptomyces avermitilis) strain, method for separating avermectin complexe s and preparations for protecting plants and animals
EP2886640A1 (en) 2013-12-18 2015-06-24 Riga Technical University Process for isolation of milbemycins A3 and A4

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992551A (en) * 1972-06-08 1976-11-16 Sankyo Company Limited Antisiotic substances B-41, their production and their use as insecticides acaricides
US3966914A (en) * 1972-06-08 1976-06-29 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
JPS4914624A (en]) * 1972-06-08 1974-02-08
US3984564A (en) * 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3998699A (en) * 1972-06-08 1976-12-21 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3992527A (en) * 1972-06-08 1976-11-16 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3992552A (en) * 1972-06-08 1976-11-16 Sankyo Company Limited Antibiotic substance B-41, their production and their use as insecticides and acaricides
JPS5645890B2 (en]) * 1973-05-29 1981-10-29
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4173571A (en) * 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
AU7191881A (en) * 1981-06-17 1983-06-30 Merck & Co., Inc. Trioxatetracyclo pentacostetraene-12-spiro-methyloxane

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0341848U (en]) * 1989-08-31 1991-04-22

Also Published As

Publication number Publication date
AU3081484A (en) 1984-11-08
NZ194742A (en) 1982-12-07
IL60861A0 (en) 1980-10-26
FR2463773A1 (fr) 1981-02-27
IL60861A (en) 1983-09-30
ES494435A0 (es) 1981-06-16
ES8106177A1 (es) 1981-06-16
IT1209436B (it) 1989-07-16
GB2056986B (en) 1983-10-19
GB2056986A (en) 1981-03-25
NL8004791A (nl) 1981-02-25
HU189473B (en) 1986-07-28
US4346171A (en) 1982-08-24
AU536200B2 (en) 1984-04-19
DE3031756C2 (en]) 1989-11-23
MX6259E (es) 1985-02-18
AU574695B2 (en) 1988-07-14
BR8005337A (pt) 1981-03-04
JPS5632481A (en) 1981-04-01
AU6166880A (en) 1981-03-05
FR2463773B1 (en]) 1984-02-24
SU1011055A3 (ru) 1983-04-07
DE3031756A1 (de) 1981-03-12
IT8068315A0 (it) 1980-08-25
CH645899A5 (de) 1984-10-31

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